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Intracytoplasmic Morphologically Selected Sperm Injection (IMSI)

During an IVF treatment, it may result in one or more embryos. However, it is safer to transfer one or two at a time. If multiple embryos are transferred, the risk of high-order multiple pregnancy increases.

Hence, to decrease this risk two to three embryos are transferred into the uterus and remaining embryos are preserved through cryopreservation for future use.

Intracytoplasmic Morphologically Selected Sperm Injection (IMSI)

What are the steps involved in the IMSI procedure?

  1. An embryologist prepares a fresh or frozen semen sample on the day of the procedure.
  2. Under a high magnification microscope such as 6,600X, an ICSI and IMSI technique specialist selects a single sperm for injection.
  3. After the egg collection, the eggs are washed and analyzed to determine the mature eggs for injection.
  4. Using a thin glass needle, the sperm is suctioned and then injected into the suitable/selected egg.
  5. In a sterile culture dish, the injected eggs are cultured overnight.
  6. Furthermore, the resultant embryos are transferred in the uterus as in the IVF process.

Who is eligible for IMSI?

IMSI has applied in conditions wherein male has poor sperm motility, poor sperm morphology, low sperm count and surgically recovered sperm.

This method has a success rate similar to ICSI.


Following are the best IVF doctors in Mumbai to perform IMSI:


Dr. Mohit R. Saraogi
Dr. Mohit R. Saraogi
Dr. Tejswita Rajpal Hande
Dr. Tejswita Rajpal Hande